|Syllabus reference (October 2002 version)|
9. ATP used in muscle contraction is continually regenerated
Students learn to:
identify NADH and FADH2 as compounds essential for respiration
describe the NADH/FADH2 oxidation as part of an oxidation–reduction process leading to ATP production
Note the different arrangement of information compared with that for glycolysis and oxidative decarboxylation in the flowchart. Hydrogens at the top react with oxygen from the left to form water at the right. Energy released by this oxidation causes phosphorylation of ADP to ATP.
2H+ + O2 + 2e- → H2O
The two diagrams should be similar. However, you may like to note that the NADH oxidation releases 3 ATP whereas the FADH2 oxidation releases only 2 ATP.
construct an equation to summarise the reduction/oxidation process in ATP regeneration
NADH + H+ + __ADP + __Pi + 1/2 O2 → NAD+ + __ATP + H2O
FADH2 + __ADP + __Pi + 1/2 O2 → FAD + __ATP + H2O .
define oxidative phosphorylation as the process that couples the oxidation of NADH and FADH2 to the production of ATP
|Processes||No. molecules produced|
|Step 1. Glycolysis of one glucose||?||?|
|Step 2. Two pyruvic acid → acetyl CoA||?|
|Step 3. Two turns of the TCA cycle||?||?||?|
|Step 4. Oxidative phosphorylation|
|No. of ATP produced from each NADH||?||?|
|No. of ATP produced from each FADH2||?||?|
|Total ATP from one glucose after completion of the four steps||?|